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Peer-Reviewed Article March 21, 2012

Evaluation of antibacterial activity of Morinda citrifolia, Vitex trifolia and Chromolaena odorata

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Published in: African Journal of Pharmacy and Pharmacology
Publisher: Academic Journals • Nigeria • 1996-0816
DOI: https://doi.org/10.5897/ajpp11.435

Abstract

Methanol, ethanol and ethyl acetate extracts of Morinda citrifolia L. (fruit, leaf and stem), Vitex trifolia and Chromolaena odorata (leaf) were prepared to evaluate the anti-bacterial activity. The antibacterial activities of extracts were tested against 12 bacterial isolates by in vitro disc diffusion method. Methanol extracts possessed higher level of antibacterial activity than ethanol and ethyl acetate extracts. When the plants were compared, C. odorata had better antibacterial activity than V. trifolia and M. citrifolia with the minimal inhibitory concentration (MIC) of about 25 mg/ml.   Key words: Antibacterial activity, disc diffusion method, Chromolaena odorata, Morinda citrifolia L., Vitex trifolia.

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