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Peer-Reviewed Article May 31, 2024

Effective Management of Acute Aluminum Phosphide Poisoning in Pregnancy: A Case Study of Dual Therapy Efficacy and Collaborative Care

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Published in: Journal of the Medical Research Institute
Publisher: Alexandria University, Medical Research Institute • Egypt • 1110-0133 • 2682-2547
DOI: https://doi.org/10.21608/jmalexu.2024.281601.1017

Abstract

Aluminum phosphide (AlP) poisoning is a significant public health concern, particularly in developing countries where it is easily accessible. This case report discusses the successful management of acute AlP poisoning in a pregnant woman at 28 weeks gestation. Initially presenting with vomiting and abdominal pain and discomfort, the patient remained stable throughout. Metabolic acidosis, identified through arterial blood gas analysis, prompted bicarbonate administration. The application of dual therapy with N-acetylcysteine (NAC) and Coenzyme Q10 (CoQ10) effectively countered oxidative stress, contributing to the patient's stabilization. Collaborative interdisciplinary care played a crucial role in ensuring the well-being of both the mother and fetus, ultimately resulting in a favorable outcome upon discharge. This case highlights the effectiveness of therapeutic interventions and underscores the pivotal importance of interdisciplinary cooperation in managing acute AlP poisoning. Such instances reinforce the significance of a rapid and coordinated response to mitigate the potentially fatal consequences of poisoning incidents.

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