Peer-Reviewed Article January 17, 2008
SAGES Guidelines Committee
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Published in: South African Gastroenterology Review
Publisher: African Journals OnLine • South Africa • 1812-1659
Abstract
Chronic hepatitis B virus infection remains a global problem of staggering proportions. It is estimated that 350 million people worldwide are chronically infected with the hepatitis B virus (HBV) and sub-Saharan Africa remains a high prevalence region. Most carriers will not develop significant hepatic disease but 15 - 40 % will develop serious sequelae during their lifetime.