Peer-Reviewed Article December 31, 2011
The Stochastic Evolution of a Protocell: The Gillespie Algorithm in a Dynamically Varying Volume
Are you an author of this work?Link to your sovereign AfriScholar profile
Published in: Computational and Mathematical Methods in Medicine
Publisher: Hindawi Publishing Corporation • Egypt • 1748-670X
Abstract
We propose an improvement of the Gillespie algorithm allowing us to study the time evolution of an ensemble of chemical reactions occurring in a varying volume, whose growth is directly related to the amount of some specific molecules, belonging to the reactions set. This allows us to study the stochastic evolution of a protocell, whose volume increases because of the production of container molecules. Several protocell models are considered and compared with the deterministic models.